Thursday, November 26, 2020
Home News Reports Human clinical trials for potential Coronavirus vaccines begin in the UK, Germany and USA,...

Human clinical trials for potential Coronavirus vaccines begin in the UK, Germany and USA, China races ahead with second phase trials

At present, there is no vaccine or known cure for the disease, although various drugs have been used by doctors with some success.

As the world races to develop vaccines for Novel Coronavirus, the UK and Germany are set to begin human trials of different vaccines for the Chinese virus. As per reports, out of around 150 projects across the world for Coronavirus vaccine, the UK and Germany projects are among the first to be approved for clinical trials on humans.

On Thursday, volunteers at a trial conducted in Oxford University will be given the first dose of a potential vaccine developed by the university that is based on a virus found in chimpanzees. The trial, run by the university’s Jenner Institute and the Oxford Vaccine group, will involve 510 volunteers aged between 18 and 55 in the first phase. Apart from being funded by the university, the project will also receive a funding of £20 million from the British government.

Even though the human trials are yet to begin, plans for mass production of the vaccine have already started, so that it is immediately available after it proves effecting in the trial. But if the vaccine is found useless in the trial, the products will go waste. The Oxford trial will be a part of a nationwide effort in the UK which has been spearheaded by Government task force.

The UK government will invest 20 million pounds (24 million dollars) to the university’s team for research and other 22.5 million pounds for Imperial college which is also developing a vaccine. The University had previously said that the aim is to produce a million doses of vaccine by September.

Secretary of state for Health and Social Care Matt Hancock praised both the teams for making the “rapid progress” and said the UK will throw “everything we’ve got at developing a vaccine.

Matt Hancock said, “We are going to back them to the hilt and give them every resource that they need to get the best possible chance of success as soon as possible. The upside of being the first country in the world to develop a successful vaccine is so huge that I am throwing everything at it.”

The experimental product develped by the team at Oxford University is called “ChAdOx1 nCoV-19”, which is a type of immunisation known as a recombinant viral vector vaccine.

Human trials in Germany

Meanwhile, the German regulatory body PEI green-lighted the country’s first trial on human volunteers for a vaccine developed by German firm Biontech and US giant Pfizer on Wednesday.

As per reports, the first phase will see 200 volunteers vaccinated with the variants of the vaccine while the second phase will include volunteers in the high-risk group. Research director Professor Sarah Gilbert stated that the trail has a 80 percent chance of being successful.

BioNTech said it was developing the potential vaccine, named BNT162, together with US based pharmaceutical giant Pfizer. Human trials for BNT162 will also be conducted in US, after regulatory approvals are obtained.

The German regulatory body PEI noted it as a significant step in making a vaccine available at the earliest. They said that testing would be completed by June, at the earliest. After this stage is complete, the PEI will determine if the vaccine can progress to further trial stages.

China races ahead with thee potential vaccines

China, the origin of the Novel Coronavirus, has developed several different vaccine candidates, and has already moved to the second phase of trial for some of them. Chinese biotech company CanSino and its collaborators at the Academy of Military Medical Sciences’ Institute of Biotechnology are planning to move forward to the second phase of trial of their adenovirus type-5 vector-based recombinant COVID-19 vaccine, Ad5-nCoV. The first phase had commenced in March.

Human trials have been approved for another vaccine developed by Sinovac Biotech andthe Wuhan Institute of Biological Products, an affiliate of state-owned China National Pharmaceutical Group.

A team at the National Institutes for Food and Drug Control in Beijing has developed another vaccine candidate based on a strain of a Wuhan Coronavirus extracted from a patient in Zhejiang. The preclinical trials done on non-human primates have shown that when given at a sufficient dose, it could provide “complete protection against Sars-CoV-2”, the virus that causes the COVID-19.

Other Trials approved

Several other potential vaccines against coronavirus are under development in various countries, and

US drug developer Moderna started human tests for their vaccine last month, and now the volunteers are given the second shot of the drug. The vaccine, called mRNA-1273, was developed by scientists at the National Institute of Allergy and Infectious Diseases in collaboration with Moderna.

Human clinical trial has also begun for another candidate developed by Inovio Pharmaceuticals along with the University of Pennsylvania’s research facility and the Wistar Institute in the USA. The group has been working on the vaccine since January, and the work was fast-tracked after the Chinese government made the genome sequencing of COVID-19 public. Approximately 40 people will be tested during the initial phase of the testing of the vaccine.

The coronavirus pandemic has infected 2.66 million people across the world and has claimed the lives of more than 185,000 people. At present, there is no vaccine or known cure for the disease, although various drugs have been used by doctors with some success.

  Support Us  

Whether NDTV or 'The Wire', they never have to worry about funds. In name of saving democracy, they get money from various sources. We need your support to fight them. Please contribute whatever you can afford

OpIndia Staffhttps://www.opindia.com
Staff reporter at OpIndia

Related Articles

Trending now

Caravan Magazine asked us about our coverage on Wikipedia and its Left bias – Here is our detailed response

OpIndia coverage of Wikipedia lies started after Delhi Riots and Caravan Magazine, with its strong Left bias, is clearly not happy about it

‘Sant’ Rampal’s devotees have been flooding social media to tell Muslims how they don’t know Islam. Read bizarre details

Born in 1951 as Rampal Singh Jatin in Punjab, the 69-year-old self-styled godman is currently lodged in Hisar central jail for murder charges.

Odisha: Largest ever vigilance raid in state unearths massive wealth gathered by IFS officer, fancy cars, ultra-luxurious lifestyle

Pathak's family reportedly owns a lavish apartment in Bhubaneswar with Italian marble flooring, ivory furnitures and other luxuries. The son is engaged to an MLA's daughter.

Germany expresses concern after corporate dependency on China increases

While German companies are happy that Chinese sales offset the fewer units sold in European countries amid the pandemic, they are also being cautious.

Lucknow: Two medical colleges run by MMA Faridi and Mohammad Zafar Idris respectively, accused of organ trafficking, probe ordered

Probe has been ordered against Era’s Medical College and Integral Institute of Medical Science And Research over Human Organ Trafficking charges

Indian law never defined “marriage”: Here is why govt needs to be involved in inter-faith “marriage”

A number of very different legal institutions are grouped under the loose word “marriage.” Naturally therefore, the government has to step in and make rules about how to move between these very different institutions.

Recently Popular

Hyderabad elections: Owaisi makes ‘beef biriyani’ sly on BJP leaders, Raja Singh offers him pork biriyani

As an insult to BJP leaders, Owaisi had stated that they should have some biriyani at a particular hotel in Hyderabad that is famous for beef dishes.

How Congress lost Gujarat to save Ahmed Patel’s Rajya Sabha seat

The 2017 Gujarat Rajya Sabha elections which were contested by Ahmed Patel were one of the lowest points for Congress.

‘Mark of religious oppression, caste superiority’: Newly elected MP in New Zealand, Gaurav Sharma, targeted for taking oath in Sanskrit

A journalist in New Zealand targeted newly elected New Zealand MP Gaurav Sharma for for taking his oath in Sanskrit.

When Sonia Gandhi trusted Ahmed Patel for conveying to PV Narasimha Rao’s family that his funeral will not be held in Delhi

Sanjaya Baru had said Ahmed Patel approached him to let PV Narasimha Rao's son know about Sonia Gandhi's message.

Remembering the role Barkha Dutt played in endangering the lives of 100s of civilians during the 26/11 Mumbai terror attack

A look back at how live coverage by journalists like Barkha Dutt and other journalists endangered lives of thousands of people during 26/11 Mumbai terror attack.

Fact Check: Did Arfa Khanum Sherwani eat the goat she was petting in the photographs she posted?

Arfa Khanum Sherwani took social media by storm after she posted photographs of herself with a beautiful white goat.
- Advertisement -

Caravan Magazine asked us about our coverage on Wikipedia and its Left bias – Here is our detailed response

OpIndia coverage of Wikipedia lies started after Delhi Riots and Caravan Magazine, with its strong Left bias, is clearly not happy about it

‘Sant’ Rampal’s devotees have been flooding social media to tell Muslims how they don’t know Islam. Read bizarre details

Born in 1951 as Rampal Singh Jatin in Punjab, the 69-year-old self-styled godman is currently lodged in Hisar central jail for murder charges.

Enforcement Directorate arrests Shiv Sena MLA Pratap Sarnaik’s aide in connection with multi-crore MMRDA security deal

Shiv Sena MLA Pratap Sarnaik's aide Chandole was grilled by ED officials for nearly 12 hours before being placed under arrest.

Fact check: Did Congress remove Ahmed Patel’s profile from its website within hours of his demise

While fact-checkers claim that Congress didn't delete Ahmed Patel's profile from its website, evidences show it was deleted and then restored

As Congress remembers the 26/11 Mumbai attacks anniversary, netizens remind the grand old party of its double standards

Rahul Gandhi was found partying at a friend's house soon after the Mumbai attacks.

Six Pakistani cricketers test positive for Coronavirus in New Zealand, NZ authorities say they breached isolation protocols

New Zealand Cricket has revealed that few members of the Pakistan party breached the protocols on the first day of managed isolation.

Odisha: Largest ever vigilance raid in state unearths massive wealth gathered by IFS officer, fancy cars, ultra-luxurious lifestyle

Pathak's family reportedly owns a lavish apartment in Bhubaneswar with Italian marble flooring, ivory furnitures and other luxuries. The son is engaged to an MLA's daughter.

Germany expresses concern after corporate dependency on China increases

While German companies are happy that Chinese sales offset the fewer units sold in European countries amid the pandemic, they are also being cautious.

Lucknow: Two medical colleges run by MMA Faridi and Mohammad Zafar Idris respectively, accused of organ trafficking, probe ordered

Probe has been ordered against Era’s Medical College and Integral Institute of Medical Science And Research over Human Organ Trafficking charges

Indian law never defined “marriage”: Here is why govt needs to be involved in inter-faith “marriage”

A number of very different legal institutions are grouped under the loose word “marriage.” Naturally therefore, the government has to step in and make rules about how to move between these very different institutions.

Connect with us

245,563FansLike
489,077FollowersFollow
20,200SubscribersSubscribe